Neuroendocrine tumors (NETs) constitute a heterogeneous group of neoplasms, arising from endocrine cells within glands (adrenal medulla, pituitary, parathyroid) or from endocrine islets in the thyroid, pancreas, respiratory and gastrointestinal tracts.
- Most common tumors are:
- Gastrointestinal NETs as carcinoids and gastrinoma
- Pancreatic NETs as insulinoma, glucagonoma, VIPoma, and gastrinoma
- Bronchopulmonary carcinoids
- Sympatho-adrenal system tumors as pheochromocytoma, paraganglioma, neuroblastoma and ganglioneuroma
- Medullary thyroid carcinoma
- Other non-NETs showing overexpression of somatostatin receptors as meningiomas, medulloblastomas, pituitary tumors, supratentorial primitive neuroectodermal tumors, and hemangioblastomas.